JAK2V617F positive polycythemia vera with paroxysmal nocturnal hemoglobinuria and visceral thromboses: a case report and review of the literature

Table 2 Autoimmune inflammatory disorder panel and thrombophilia workup

Autoimmune inflammatory disorder panel		Thrombophilia workup
ΑΝΑ	> 1:640 AC-4	factor V (Leiden) gene mutation	negative
anti-ENA-La	positive	G20210A factor II gene mutation	negative
anti-ENA-Ro	negative	AT deficiency	negative
anti-ENA-RNP	negative	protein C deficiency	negative
anti-ENA-Sm	negative	protein S deficiency	negative
p-ANCA	negative	MTHFR	C677T homozygosity
c-ANCA	negative	blood homocysteine level	7 μmol/L (NR 5–15 μmol/L)
anti-dsDNA	negative	aCL and anti-β 2-GPI antibodies	negative
AMA	negative
ASMA	negative

ANA Antinuclear antibody, AC-4 Anti cell-4 pattern, ENA Extractable nuclear antigen, RNP Ribonucleoprotein, Sm Smith, p-ANCA Perinuclear anti-neutrophil cytoplasmic antibodies, c-ANCA Antineutrophil cytoplasmic antibodies, dsDNA Double stranded DNA, AMA Antimitochondrial antibodies, ASMA Anti-smooth muscle antibody, AT Antithrombin, MTHFR Methylenetetrahydrofolate reductase, aCL Anti-cardiolipin, β2-GPI Beta-2-glycoprotein I, NR Normal range

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