Table 2 Haemostasis parameters
| COVID-19 | Sepsis | P value | |
|---|---|---|---|
| Standard laboratory values | |||
| Hb, g/dl (normal, 13.7–17.2) | 9.5 ± 1 | 8.3 ± 1.5 | |
| Plts, x 109/l (normal, 140–320) | 272 ± 152 | 140 ± 90 | |
| INR | 1.16 ± 0.16 | 1.20 ± 0.28 | |
|
aPTT, s (normal, 24.4–32.4) Heparin dose, IU/h, range (mean) |
43 ± 12.9 400–1200 (730) |
32 ± 7.6 400–1000 (480) | |
|
Fibrinogen, mg/dl (normal, 188–384) | 757 ± 135 | 498 ± 132 | < 0.0001 |
| D-dimer, mg/l (normal, < 0.52) | 16.4 ± 10.7 | 5.4 ± 6.0 | 0.14 |
| EXTEM | |||
|
*CT, s (normal, 38–79) Median 25 % percentile − 75 % percentile |
90.5 76.2–104.5 |
81 67.3–93.3 | 0.112 |
|
*CFT, s (normal, 34–159) Median 25 % percentile − 75 % percentile |
58 47.8–81.5 |
76 54.3–139.8 | 0.066 |
| A10, mm (normal, 43–65) | 64.6 ± 12.3 | 54.7 ± 16.4 | 0.076 |
| MCF, mm (normal, 50–72) | 70.4 ± 10.4 | 60.6 ± 14.8 | 0.022 |
| ML % 60 (normal, 6 %-10 %) | 0.6 ± 1.2 | 3.3 ± 3.7 | 0.013 |
| INTEM | |||
|
*CT, s (normal, 100–240) Median 25 % percentile − 75 % percentile |
293.5 220.8–429.5 |
232.5 188.3–248 | 0.016 |
|
*CFT, s (normal, 30–110) Median 25 % percentile − 75 % percentile |
66.5 54–129.8 |
79 53.3–128.5 | 0.888 |
| A10, mm (normal, 44–66) | 62 ± 15 | 54.5 ± 16 | 0.158 |
| MCF, mm (normal, 50–72) | 68.6 ± 11.4 | 59.2 ± 15.8 | 0.057 |
| FIBTEM | |||
| MCF, mm (normal, 9–25) | 38.4 ± 10.1 | 29.6 ± 10.8 | 0.012 |
| APTEM | |||
|
*CFT, s (normal, 35–160) Median 25 % percentile − 75 % percentile |
56 45.5–70.5 |
86.5 60.3–123 | 0.02 |
| MCF, mm (normal, 53–72) | 69.1 ± 11 | 56 ± 15.2 | 0.003 |