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Recurrent VTE
N = 32
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No recurrent VTE
N = 24
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Total
N = 56
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Odds ratio (95% CI)
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|---|
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Villalta score [15]
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5.55 ± 3.02
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5.26 ± 2.63
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5.43 ± 2.84
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–
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- Subjective score
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1.63 ± 1.43
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2.22 ± 2.30
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1.87 ± 1.85
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–
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- Objective score
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4.03 ± 3.07
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3.08 ± 1.74
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3.62 ± 2.60
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–
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Post-Thrombotic syndromea [15, 17]
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20 (62.5)
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14 (58.3)
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34 (60.7)
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1.19 (0.40–3.51)
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- None (0–4)
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11 (34.4)
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9 (37.5)
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20 (35.7)
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0.87 (0.29–2.63)
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- Mild (5–9)
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17 (53.1)
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11 (45.8)
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28 (50.0)
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1.34 (0.46–3.87)
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- Moderate (10–14)
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3 (9.4)
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3 (12.5)
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6 (10.7)
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0.72 (0.13–3.95)
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- Severe (≥15 or venous ulceration)
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0 (0.0)
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0 (0.0)
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0 (0.0)
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0.75 (0.01–39.3)
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- Missing
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1 (3.1)
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1 (4.2)
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2 (3.6)
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0.74 (0.04–12.5)
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SF-36b − Reported health transition
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51.7 ± 18.5
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52.1 ± 14.6
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51.9 ± 16.7
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–
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VEINES QOL/Symc
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49.5 ± 11.1
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51.5 ± 8.2
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50.4 ± 9.9
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–
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VEINES QOL/Sym, intrinsic scored
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71.3 ± 14.8
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72.4 ± 12.2
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71.8 ± 13.6
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–
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- Data are n (%) or mean ± SD
- None of the variables mentioned in this table showed statistical significant difference between groups
- VTE Venous thrombo-embolism
- a Post-thrombotic syndrome was defined according to the definition stated by the International Society of Thrombosis and Haemostasis. This definition requires a single Villalta-score ≥ 5 assessed at 6 months or more after the acute venous thrombo-embolic event [17]
- bThe SF-36 is a questionnaire aimed at the generic health-related quality of life as reported by the patients. It comprises 36 questions covering 8 different health-related dimensions: Physical functioning, Role limitations due to physical health, Role limitations due to emotional health, Energy/Fatigue, Emotional well-being, Social functioning, Bodily pain, and General health perceptions [18]
- cThe VEINES QOL/SYM is a questionnaire addressing the disease-specific self-reported quality of life in DVT patients. It entails 25 questions regarding the limitations, symptoms, and changes encountered as a result of the acute thromboembolic event. The final summarizing score is adapted to the study population [19, 20]
- dBy using the method by Bland et al. [21] the VEINES QOL/SYM summarizing score can be transformed into an intrinsic score which allows comparison to other quality of life scores
