From: Effect of sinus rhythm restoration on markers of thrombin generation in atrial fibrillation
| Variable | AF patients (n = 13) | Reference group (n = 49) | p |
|---|---|---|---|
| Medical history | |||
| Age (years) | 59 ± 12 | 62 ± 0 | 0.298 |
| Sex (women/men) | 4/9 | 20/29 | 0.509 |
| Body mass index (kg/m2) | 25 ± 3 | 26 ± 4 | 0.253 |
| Hypertension | 2 (15%) | 18 (37%) | 0.192 |
| Coronary heart disease | 1 (8%) | 2 (4%) | 0.513 |
| Diabetes | 1 (8%) | 4 (8%) | 1.0 |
| Chronic obstructive pulmonary disease | 0 | 1 (2%) | 1.0 |
| Current cigarette smoking | 3 (23%) | 7 (14%) | 0.432 |
| Medication | |||
| Angiotensin receptor blocker/study drug | 6 (46%) | 13 (27%) | 0.192 |
| Angiotensin-converting enzyme inhibitor | 0 | 1 (2%) | 1.0 |
| Beta-blockers | 3 (23%) | 4 (8%) | 0.153 |
| Calcium channel blockers | 3 (23%) | 4 (8%) | 0.153 |
| Diuretics | 0 | 4 (8%) | 0.571 |
| Statins | 1 (8%) | 11 (22%) | 0.431 |
| Antiplatelet therapy | 2 (15%) | 5 (10%) | 0.630 |
| Blood pressure and heart rate | |||
| Systolic blood pressure (mmHg) | 129 ± 18 | 134 ± 15 | 0.326 |
| Diastolic blood pressure (mmHg) | 78 ± 6 | 78 ± 8 | 0.779 |
| Ventricular heart rate (beats per minute) | 59 ± 7 | 64 ± 10 | 0.072 |