Table 1 Distribution of 10 clinically and 5 genetically relevant variables in a cohort of young women at baseline of the observational period 1993 – 2003. The total number of women in this analysis is 4320, i.e. excluding 17 women with a final diagnosis of a possible/potential VTE. Deviations from this number are due to missing data
From: VTE Risk assessment – a prognostic Model: BATER Cohort Study of young women
| Variables | |||
|---|---|---|---|
| Continuous variables | n | Mean (SD) | |
| Age (years) | 4320 | 26.0 (8.6) | |
| Life births, number | 1910 | 1.7 (0.8) | |
| BMI§ | 4309 | 23.3 (4.1) | |
| Protein C (unit/dl) | 4315 | 102.4 (15.8) | |
| AT III (unit/dl) | 4316 | 98.4 (11.3) | |
| Categorical parameters | Percent (%) | ||
| Own history of VTE | No | 4279 | 99.0 |
| Yes | 41 | 1.0 | |
| Family history | No | 3840 | 88.9 |
| Yes | 480 | 11.1 | |
| Age, alternative | <30 | 2843 | 65.8 |
| ≥ 30 | 1477 | 34.2 | |
| Family history of varicous veins | No | 2395 | 55.4 |
| Yes | 1925 | 44.6 | |
| Family history of MI | No | 3830 | 88.7 |
| Yes | 490 | 11.3 | |
| BMI, alternative | <25 | 3218 | 74.7 |
| ≥ 25 | 1091 | 25.3 | |
| Ever use of hormone replacement | No | 4031 | 93.7 |
| Yes | 270 | 6.3 | |
| Family history of stroke | No | 4013 | 92.9 |
| Yes | 307 | 7.1 | |
| Ever use of oral contraceptives | No | 346 | 8.0 |
| Yes | 3973 | 92.0 | |
| Education level: University entrance diploma | No | 3119 | 73.2 |
| Yes | 1139 | 26.8 | |
| Ever smoker | No | 2022 | 46.8 |
| Yes | 2296 | 53.2 | |
| Laboratory parameters | |||
| Factor V Leiden mutation1 | No | 4035 | 93.7 |
| Yes | 271 | 6.3 | |
| Prothrombin mutation1 | No | 4088 | 96.6 |
| Yes | 142 | 3.4 | |
| MTHFR1 | No | 1798 | 42.5 |
| Yes | 2432 | 57.5 | |
| Protein C: ≥ 77(unit/dl) | No | 4117 | 95.4 |
| <77 (5th percentile; unit/dl) | Yes | 198 | 4.6 |
| AT III: ≥ 81(unit/dl) | No | 4106 | 95.1 |
| <81 (5th percentile; unit/dl) | Yes | 210 | 4.9 |