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Table 1 Characteristics of main Activated Clotting Time (ACT) instruments for high-dose heparin therapy.

From: Point-of-Care Testing of Hemostasis in Cardiac Surgery

INSTRUMENT (Manufacturer) ASSAY ACTIVATORS SAMPLE SIZE SAMPLE TYPE
HEMOCHRON Series (ITC, USA) ACT Celite or Kaolin 2 mL FWB
HEMOCHRON JR II and SIGNATURE (ITC, USA) ACT+ Kaolin, silica and phospholipids 1 drop FWB
ACT II, HEPCON HMS (Medtronic, USA) ACT, HEMOSTATUS Kaolin or celite 0.4 mL (×2) FWB
RAPIDPOINT COAG (Bayer, USA) HMT Celite 1 drop FWB CWB
I-STAT (ABBOTT, USA) Celite-ACT Celite 40 microL FWB
COAGUCHEK PRO (Roche Diagnostics, USA) ACT Celite 1 drop FWB
ACTALYKE (ARRAY 1) ACT 1) Celite or kaolin 1) 1 mL FWB
MEDICAL, USA) 2) MAX-ACT 2) Celite, kaolin and glass cocktail 2) 0.5 mL  
SONOCLOT (Sienco, USA) SONACT Celite 0.4 mL FWB CWB
  1. ACT, activated clotting time; FWB, fresh whole blood; CWB, citrated whole blood.